Common Questions

Edex (alprostadil for injection) is an injectable option for men who do not respond to, or are not candidates for, oral erectile dysfunction therapy.¹

Edex is indicated for the treatment of erectile dysfunction due to neurogenic, vasculogenic, psychogenic, or mixed etiology. Edex is supplied in a convenient dual-chamber injection system and does not require refrigeration.

References:

1. Montorsi F, Salonia A, Deho F, et al. Pharmacological management of erectile dysfunction. BJU Int. 2003;91(5): 446-54.

The active ingredient in Edex (alprostadil for injection) is alprostadil.

Alprostadil is identical to a naturally occurring substance in the body. Alprostadil widens the blood vessels and increases blood flow into the penis.

Once Edex (alprostadil for injection) is administered, you can expect it to take effect in 5 to 20 minutes.

The standard goal for treatment is to produce an erection that lasts no longer than one hour. If you still have an erection six hours after injection, call your doctor immediately or, if your doctor is not available, seek professional help elsewhere.

You can use Edex (alprostadil for injection) three times a week. The injections should be administered at least 24 hours apart. You should NOT use Edex more than three times a week. Ideally, the injection should be given just prior to foreplay.

In two studies with more than 300 patients with erectile dysfunction, the rate of response producing an erection sufficient for sexual intercourse was over 85 percent.  The most common side effect with Edex was penile pain, experienced by 31 percent of patients compared to 9 percent of patients who received placebo. 

Yes. Edex was approved by the FDA in 1997.

Edex has been effectively used to treat men with ED for more than 10 years.

Erections that last more than 6 hours can cause serious damage to the penile tissue and may result in permanent impotence. Call the prescribing physician or seek professional help immediately if you still have an erection 6 hours after the injection.

A common side effect is mild to moderate pain during the injection. The erection may also be associated with penile pain. If you experience severe pain, call the doctor who prescribed Edex.

A small amount of bleeding or bruising at the injection site may occur. To prevent bruising, apply firm pressure to the injection site for five minutes. Continue until bleeding stops. Tell your doctor if you have a condition or are taking a medicine that interferes with blood clotting.

Call your doctor if you see any redness, lumps, swelling, tenderness or curvature of the erect penis.

There is the possibility of needle breakage. To best avoid this, follow your doctor's instructions for proper injection technique. If needle breakage occurs, contact your doctor immediately.

To ensure safe and effective use of Edex (alprostadil for injection), you should be thoroughly instructed and trained in the self-injection technique before you begin intracavernous treatment with Edex at home. 

Be sure to use only the dose prescribed by your doctor. Before you begin your self-injection procedure, please read the instructions.

Edex (alprostadil for injection) has been effectively used to treat men with ED for more than 10 years.

The National Institutes of Health estimates that ED affects as many as 30 million men in the United States.¹

The condition is common and can be caused by many health-related issues, including cardiovascular disease, diabetes, neurological problems, hormonal imbalances and drug side effects.

Reference:

1. National Institutes of Health (NIH) Consensus Conference. NIH Consensus Development Panel on Impotence. Impotence. Journal of the American Medical Association. 1993;270:83–90. Erectile Dysfunction Information: link to National Institutes of Health website

It is important to communicate openly about the use of Edex (alprostadil for injection). This is a medical decision that affects both of you. Explain to your partner how Edex works.

Talk to your physician if you need further guidance.

If you have questions about Edex, talk to your doctor. Your personal physician is always your best source of health information.

For more information, download our Patient Information Brochure.

Men who have conditions that might result in long-lasting erections should not use Edex (alprostadil for injection). Some of these conditions are sickle cell anemia or trait, leukemia and tumor of the bone marrow (multiple myeloma).

If you have any of these conditions, talk to your doctor. Men with penile implants, severe penile curvature or those who have been advised not to engage in sexual activity should not use Edex.

Edex should not be used by women and children.

Please talk to you doctor to see if Edex is right for you.

Edex is not a cure for erectile dysfunction. The underlying treatable medical causes should be diagnosed and treated prior to starting therapy. The therapeutic effect of each dose is temporary.

Actient is a specialty pharmaceutical company dedicated to serving patients with therapies like Edex (alprostadil for injection). 

To learn more about Actient Pharmaceuticals, visit our website here.